Seiko Steel Structure (600496) Company Comments: Pre-Order for Assembly General Contracting Business Increases, and Forecast of Results Meets Expectations

Seiko Steel Structure (600496) Company Comments: Pre-Order for Assembly General Contracting Business Increases, and Forecast of Results Meets Expectations
Orders have steadily increased, and policies have pushed assembly steel structures to meet new changes. Soon, the company announced its 2019 business briefing.The company’s cumulative undertaking amount is 140.42 ppm, an increase of 14 over the same period last year.45%.Among them, the public construction sector and industrial construction business increased by 84 compared with the same period last year.70%, 14.12%.The company signed new orders of over 100 million yuan in 201961.2 billion, an annual increase of 29.6%, of which public, industrial, commercial construction orders over 10,000 yuan growth rate were 143.4%, 19.3%, 10%.The significant improvement of the company’s public 上海夜网论坛 construction sector is mainly due to the company’s search for upgrades based on the traditional steel structure subcontracting model. The shift from the professional subcontracting model to the EPC general contracting model has brought about an increase in the company’s business undertaking scale and orders of 100 million yuan. Under the background of the Ministry of Housing and Construction vigorously promoting the prefabrication of steel structures, Zhejiang Province has issued the “Evaluation Standards for Prefabricated Buildings”, which requires that the prefabrication rate of prefabricated buildings reaches 50% or more.advantageous.As of the end of 2019, the company has opened up six major regional markets through the technology joining model.At the beginning of January, it undertook two projects: “New Shaoxing Sports 武汉夜网论坛 School EPC Project” and “Mirror Lake Headquarters EPC Project”, with a total contract value of 6.8.5 billion.In the future, we can continue to look forward to the advancement of the company’s green building GBS technology and the transformation of results. The prefabricated construction business is leading the technology, and the method of joining technology broadens the profit channel. On January 10, 2020, the company’s “High-rise Steel-Concrete Hybrid Structure Theory, Technology and Engineering Application” project won the first prize of the National Science and Technology Progress Award, showing the companyLeading technology in prefabricated construction.At present, the company has built a complete set of technical systems for green buildings integrated with this technology, forming a five-product system of PSC residential systems, apartments, schools, hospitals, and office buildings, and opened in six places including Hebei, Shanxi, and Hunan with a technology joining model.Regional markets.This technology joining method has strong operability and rapid expansion, and the company makes profits by referring to partner technology and resource costs.This solves the regional restrictions of prefabricated buildings and widens the company’s prefabricated profit channels. Before the profit growth rate, the EPC model and prefabricated construction helped the company improve its overall gross profit margin.On the evening of January 15th, the 19-year performance forecast was released, and it is expected to realize net profit attributable to mothers in 19 years.8-4.200 million, an annual increase of 109% -131%, and the net profit growth rate of non-returned mothers is expected to be 115% -141%, which is in line with our previous expectations.The company’s median profit growth rate is relatively high, mainly due to the continuous improvement of business undertakings. At the same time, the company vigorously promotes the prefabricated construction and EPC general contracting business, and has achieved better development. The increase in the technology’s franchise model has improved the overall gross profit level.It is also continuously improving the quality of orders and strengthening the operation of projects, and there is room for continued improvement in gross profit margin. Investment suggestion We believe that the steel structure industry is booming, and the company’s contracts in hand are steadily increasing, the order structure is improving, new business development can be expected, and performance promotes high growth.The continuous business increase caused by the policy-driven assembled steel structure of the company that proposed the changes, and at the same time reported that the controlling shareholder of the merged company has changed, and the impact of the default of the Seiko Holding Group bonds on it has basically been eliminated.We maintain the EPS for 2019-2021 to 0.22, 0.26, 0.32 yuan / share, corresponding to PE, 14, 12, and 10 times, maintaining a target price of 4.40 yuan, maintain “Buy” rating. Risk warning: policy advances less than expected; steel industry boom declines

The concept of split expectations attracted attention from 920 institutions in the second half of the research focus

The concept of “split expectations” attracted attention from 920 institutions in the second half of the research focus

Source: Securities Daily reporter Zhou Shangyue On January 30 this year, the Securities Regulatory Commission issued the “Opinions on the Implementation of the Shanghai Stock Exchange to Establish a Scientific and Technological Innovation Board and the Pilot Registration System.”Eligible subsidiaries are listed on the science and technology board.

Subsequently, on August 23, the CSRC publicly solicited opinions on “Some Provisions on the Pilot Program for the Internal Listing of Spin-off Subsidiaries of Listed Companies”.

Only on more than three months later, on December 13, the CSRC officially issued the “Several Provisions on the Pilot Program for Spin-off of Listed Companies’ Subsidiary Subsidiaries”, which aroused great market attention.

  From the perspective of research, according to the statistics of Oriental Fortune Choice data, the concept of “split expectation” is very hot now.

Since the second half of the year, 920 listed companies with the concept of “split expectations” have been investigated by institutions3.

230,000 times.

Among them, the securities firm researched the highest “stiffness” and investigated a total of 8,108 times.

  Among the expected concept stocks that have been split by the institution “phase”, the most studied listed companies are Hikvision, Guanglianda, Dahua, Lepu Medical, GoerTek, Zhaoyi Innovation, HuichuanTechnology, Zhongshun Jierou, Senma Clothing, Huayu Software.

  Among them, Lepu Medical clearly stated in its 2018 annual report that “it will actively promote the integration and shareholding of the company’s artificial intelligence business companies and prepare for the science and technology board or overseas spin-off listing.”

Investors paid great attention to whether Lepu Medical could spin off its subsidiary’s listing. In response to the investor ‘s question, the secretary of Lepu Medical said: “The spin-off and listing will help Lepu Medical reshape the valuation system.The international innovation business will be estimated and priced according to international standards, allowing independent and major international innovation business of the subsidiary to have a more independent development platform, expanding the company’s financing channels, and further promoting the company’s existing business and spin-off business.Development and growth.

Regarding the official implementation of the new rules for the spin-off and listing, the assistant chairman of Ruikang Jin Jinhang told the reporter of the Securities Daily:The holder’s emerging industry assets have found organizational structures that can meet the characteristics at different stages of the life cycle and can continue to promote their development and continuity. From the aspect of internal management standards, they still seek external strategic investors from different perspectives to make the company better.This model is an innovative practice to solve the alternative development of listed companies after the split share structure reform.

“” At the same time, the new listing and separation rules will help the parent and subsidiary companies focus on their core business, which will help improve the indicator level of the subsidiary, and help listed companies to post strategic investors to emerging industry assets held at different stages of the life cycle.Financing capacity.

The new listing spin-off rules will facilitate future mixed reforms and the transformation of the original enterprise’s model from managing assets to managing capital.

Jin Qihang continued this.

  A top person pointed out, “Xinmai Medical was demolished from a Hong Kong listed company, and its market value has exceeded the market value of the Hong Kong parent company.

Although there are not many companies with qualified shares at the moment, the new rules for spin-off listing have given too many new efforts to A-share listed companies.Operational tools.

“For the investment opportunities brought about by the spin-off and listing, Zhao Qiaomin, an analyst at Guangzheng Hang Seng, believes that” the value of the spin-off and listing has been revalued in practice.

70%.

For listing, investors can pay attention to the estimated repair opportunities and conversion of A-share listed companies with intention to spin 南宁桑拿 off the listing, and still pay attention to potential Pre-IPO investment opportunities of subsidiaries of listed companies in the New Third Board, or share the long-term benefits of spin-off listingincome.

Investors are advised to make a full assessment of the need for spin-off listing transactions when selecting investment targets, to avoid the potential risks of spin-off listing transactions, and to grasp investment opportunities brought by spin-off exchanges focused on business and independent development.

Taoli Bread (603866): 1Q affected by quarterly growth rate, long-term steady expansion logic remains unchanged

Taoli Bread (603866): 1Q affected by quarterly growth rate, long-term steady expansion logic remains unchanged

1Q19 results are in line with expectations Taoli Bread announced 1Q19 results: operating income11.

400 million, +15 a 北京桑拿洗浴保健year.

52%; net profit attributable to parent company1.

21 trillion, +12 for ten years.

11%.

The performance is consistent with the performance express report, which is in line with expectations.

Development Trends 1Q19 The revenue growth is steady, and the trend is expected to continue in 19 years.

The company’s 1Q19 revenue increased by 15.

52%, even if the growth rate slightly tilted in the face of the increase in the Spring Festival operating rate and a high base during the same period, but still achieved a steady growth.

According to the operating data disclosed by the company, East China and South China achieved higher growth, with the revenue share respectively from 20 at the end of 18th.

2% / 6.

4% increased to 20.

5% / 7.

1%, while the Northeast base camp area achieved solid double-digit growth.

We expect the company to focus on new markets in eastern China, southern China, with the deepening of the marketing channel network and the increase in plant operating rates, to achieve sustained and overall growth in revenue. The Shanghai market will experience accelerated growth in raw materials after an 18-year adjustment period.The market is expected to maintain expansion and stability through measures such as channel refinement and sinking in the process of accelerating the competition to gain market share. We expect the steady growth of the company’s revenue side in 19 years to continue.

1Q19 gross margin constant +0.

5ppt, the sales expense rate is ten years +1.

3ppt.

The increase in gross profit margin was mainly driven by the upgrading of the product structure, while the expense ratio was at a relatively high level due to the settlement of expenses such as staff wages and bonuses in the first quarter and the continued expenditure of market expenses. The decrease in the operating rate during the Spring Festival led to scale effects and attenuation.Therefore, the average profit growth rate, at the same time 1Q18 return to the mother net profit increased by 51.

At the same time, a high base also puts some pressure on profit growth.

We expect that the company’s gross profit margin in 19 years will continue to benefit from the continuous optimization of the product structure and a steady increase. We expect the sales expense ratio to maintain a high level to ensure the stable increase of the company’s market share, which is conducive to market development and leveraging revenue growth.

The profit forecast is mainly due to the profit growth rate in 1Q1武汉夜网论坛 9 and the expected transmission of the company’s expenditure expenses. We have slightly reduced the company’s 19/20 EPS forecast by 3% / 3% to 1.

57/1.

8 yuan.

Estimates and recommendations The current budget corresponds to 24/21 times P / E in 19/20.

Due to the adjustment of earnings forecast and the revision of the estimated hub, the target price is reduced by 13% to 55 yuan, corresponding to 35/31 times P / E in 19/20, and there is still 48% of room for growth.

Risk area expansion risks, increased industry competition, raw material price fluctuations, and food safety risks.

Making fish soup more delicious is just three tips

Making fish soup more delicious is just three tips

Fish soup is a very nutritious tonic. To make fish soup more delicious, you need to master a few tricks!

  There are many ways to make fresh fish soup.

Here are a few of them.

  1.

Descaling the fresh fish first, remove the internal organs, clean it, put it in boiling water for three or four minutes and remove it, then put it in the boiling soup, add the appropriate amount of onion, ginger, refined salt, and use a low heat to cook slowly, When the umami tastes out of the fire, drip on the sesame oil.

  2.

Freshly washed fish, fry in oil until slightly yellow on both sides, then pour in boiling water, add onions, ginger, boil over high heat, and cook on low heat.

  3.

Remove fresh water from cleaned fish for later use.

Put the oil in the pan, use the spring onion, ginger slices, and sauté the pan. When the spring onion turns yellow and smells, pour in boiling water. After the high heat is boiled, put the fish in the high heat.can.

Can yoga help me lose weight fast?

Can yoga help me lose weight fast?

Q: I have a problem with my cervical spine due to long office work.

I heard from colleagues that yoga practice can improve this occupational disease, and I would like to try it.

But considering that you are a male, gentleness is not very good, and I am a bit worried.

I wonder if this situation is suitable for me?

  A: After the weather turned cold, more people started practicing yoga.

Regarding yoga, unfamiliar people usually have some misunderstandings, like this kind of question raised by Mr. Li.

  Many people think that a soft body is good for yoga.

actually not.

Yoga emphasizes moderation, and does not pursue the magnitude of movement completion. As long as the practitioners do their best, they can get the desired effect.

And through long-term practice, people’s softness can also be improved.

  Because most of the women who practice yoga in China make women think that yoga is the patent of women.

You know, the original inventors and practitioners of yoga were mostly men, and many well-known yoga masters were also men.

In some countries in Europe and America, even men practice yoga more extensively than women.

There is a male trainer in our hall. Although his weakness is lacking, after a few months of exercise, his movements have become more standard and the progress is very obvious.

  From the perspective of weight loss, the effect of yoga may not be immediate, but it plays an important role in our physical health.

An office worker like Mr. Li may not have an urgent need for weight loss, but instead focuses on decompression and fitness. Choosing yoga can help relieve stress by regulating endocrine, especially for cervical spine disease.

A female member with a severe cervical spinal canal problem has improved her condition through yoga practice, and the “giggle” between cervical vertebrae has also eased.

  For good results, it is important to keep practicing.

Each complete yoga exercise can help you relieve fatigue and rejuvenate, so that your entire body from the internal organs, glands to muscles, bones, and even the brain can be massaged and relaxed.

Medicinal diet therapy, teach you to eat butterfly spots

Medicinal diet therapy, teach you to “eat” butterfly spots

Butterfly spot, also called chloasma, occurs in the face of middle-aged women and pregnant women. It is a pigmented skin disease.
Appears as light brown or light black spots, mostly distributed in the forehead, eyebrows, cheeks, nose, lips, etc., generally without conscious symptoms and systemic symptoms, but it is the enemy of beauty.
  Modern medical research believes that the occurrence of butterfly spots is not only related to endocrine and metabolic disorders, certain wasting diseases, but also to diet.
Therefore, paying attention to diet conditioning is a basic method for controlling butterfly spots.
In addition to usually eat more fruits and vegetables and foods rich in vitamin C, not to eat spicy fried food, you should also use medicated diet to prevent and control.
Here are a few medicated therapies that teach you to “eat” butterfly spots.
  100 grams of soy beans, 100 grams of mung beans, 100 grams of red beans, and sugar.
Wash and dip the above three beans to fullness, mix and stir the juice, add an appropriate amount of water and boil.
Season with sugar and drink 3 times a day.
  Shenqi cream tincture 100g ginseng, 200g astragalus, 100g Ophiopogon, 50g paeony.
Shred the raw materials, add an appropriate amount of water to fry, remove the residue and extract the juice, condense with a gentle fire to form a paste, and then add honey equal to the thick paste to obtain the paste.
Take 1 tablespoon daily in the morning and evening.
  Red date radish soup with carrots 50 grams, red dates 30 grams, wolfberry 15 grams, the amount of rock sugar.
The red dates, carrots, and wolfberries are washed and placed in a pot. Add an appropriate amount of water and cook until they are ripe. Add sugar to taste and serve.
  Red dates, cherry porridge, red dates 50 grams, peanuts 30 grams, cherries 50 grams, brown sugar amount, 100 grams of japonica rice.
Soak the red dates and peanuts for 20 minutes. Put the pitted cherry and rice together in the pot to cook porridge. When the porridge is cooked, add brown sugar to taste and serve.
  Pork kidney porridge 1 pair of pig kidney (removed fascia, chopped), 200 grams of japonica rice, 100 grams of yam (peeled and chopped), and 50 grams of barley kernels.
After slicing the chopped pork kidneys with blood, add water to yam, barley kernels, and japonica rice, add the appropriate amount of salt and monosodium glutamate to the porridge with small fire, and eat.
  Mulberry honey paste mulberry 100 grams, black sesame 50 grams, Polygonum multiflorum 30 grams, angelica 20 grams, 20 grams of Ophiopogon, 20 grams of habitat.
Put the medicine into the pot together, add an appropriate amount of water, cook for 30 minutes to extract the medicine once, repeat 3 times, and then combine the 3 times, condense to a thick paste, add honey 1 times, mix again, and mix againBoil and cool in tins after cooling.
1 spoon at a time, rinse with boiling water, take morning and evening.
  300 grams of walnut milk, walnut kernel, 200 grams of milk, 200 grams of soy milk, 200 grams of black sesame.
Put walnut kernel, sesame, milk and soy milk in a blender and stir. After boiling, add a small amount of sugar to taste, or you can stir in raw eggs while boiling.
Take 1 small bowl twice a day, morning and evening.
  Qibai Beauty Cake: 50 grams of white lentils, 50 grams of white lotus seeds, 50 grams of white poria, 15 grams of white chrysanthemums, 50 grams of yam, 200 grams of flour, and 100 grams of sugar.
Grind lentils, lotus seeds, Poria, yam, and chrysanthemums into fine powder, mix with flour and add fresh yeast to ferment, add white sugar when it is ready, knead into small balls and steam for 30 minutes.
  Babao Freckle Congee 10g, Coix Seed 10g, Lotus Seed 15g, Raw Yam 30g, White Lentil 10g, Chixiaodou 15g, Jujube 10g, Japonica 200g.
Except for the rice, cook for 40 minutes with the right amount of medicine and water, then put the rice with the porridge and season with rock sugar.
Take 1 small bowl each morning and evening, and Jiufu works very well.
  Betel nut liqueur 20 grams of betel nut, 20 grams of orange peel, 10 grams of green peel, 5 grams of amomum, 10 grams of rose, 1500 ml of rice wine.
Grind the medicines into coarse powder, put them into yarn bags, immerse them in rice wine, cook for 30 minutes, add a small amount of rock sugar, remove the medicine bags, and store the wine in bottles.
Take 20 ml each time, 2 times a day.
Pregnant women are prohibited.
  Astragalus braised turtle with astragalus root 50 grams, wolfberry 30 grams, turtle 500 grams.
First wrap the astragalus slices with gauze, wash the wolfberry, cut the turtle into the internal organs and cut them into the same pot. Add an appropriate amount of water.
Stew and remove the residue. Season with ginger, spring onion, monosodium glutamate, refined salt, etc. and serve.
  Manna skin juice syrup 100 grams of Sydney, 200 grams of sugar cane, 300 grams of grapes, 100 grams of honey.
Wash the Sydney juice, sugar cane, and grapes, remove the residue, and mix with honey and bottle.Take 1 tablespoon daily in the morning and evening with warm water.

  Angelica Lily Rabbit 15g Angelica, 50g Lily, 10g Tianqi, 250g rabbit meat.

Wash and chop lily, Angelica sinensis, Tian Qiyan, put it into the steaming bowl with the rabbit meat, add an appropriate amount of water, simmer until it is cooked through the water and heat, season the soup and eat the meat.

When should a couple of 9 to 5 office workers make love?

When should a couple of 9 to 5 office workers make love?

You love each other.

In his eyes, you are beautiful and you are unique.

He is the same for you.

However, how long have you not made love?

  ”Too tired”, this is your first reaction.

  Yes, 8 hours a day, and enduring the crowded traffic in the city – the only result of this life is fatigue.

Tiredness is the enemy of sexual life.

What should you do?

You have to put love in a very important position, you must arrange for sex into your life – you must find out when to make love.

Yes, time is all out, you have to know that a perfect sex can bring a good mood for a week.

Consider the following suggestions – go straight to the big bed after work, don’t make love to be done only when you sleep at night.

After eating dinner and watching TV, tiredness will gradually invade you, and the stress during the day will also work. At this time, your confused head has only one thought left: sleep.

  So, make love before dinner.

Maybe, one day a week, go straight to the big bed after going home!

  Come to a romantic date to meet a movie after work.

Even if you are in the same office, it is best to prepare them separately, go to the cinema, and have a romantic meeting in the long queue of the cinema!

Make sure your seats are in a dark corner behind you, and of course you will enjoy the movie, but it is more important to enjoy each other.

  I believe that after the movie is over, you have all entered the situation – after returning home, you will not have a second thought!

  On a special day of the week, you may have the wrong answer: making love is a natural occurrence.

You wait, wait, wait for the best moment – but it never comes.

So, it’s more sensible to pick out a day in the week as a day of sex.

In this way, on the night before, you will subconsciously rest better and prepare for this day.

Or, giving the other person a love message in advance can also fully stimulate the expectation of each other.

  How did the passion weekend weekend pass?

Many people think that leaving home is a good choice for a sexy trip.

However, sometimes this is not feasible if the economy is permanent.

Moreover, although you are looking forward to a romantic trip, you may also be going to the crowd.

Therefore, as long as there are no parents to visit, no friends to visit, it is better to enjoy the two worlds at home.

On Thursday, you can take time out to shop, make sly lights, make romantic wines, and stimulate the food of desire, but they are all must-have items.

Ok, Friday, say goodbye to everything else, put a light, mellow soundtrack, and you can start a passionate weekend.

Yoga moves show a beautiful figure

Yoga moves show a beautiful figure

Serene, relaxed yoga is most likely to make you fall in love with the bedroom at first sight.

As long as the basic elements of the bedroom are properly used: large beds, cabinets, high-back chairs . this summer you don’t need to sweat and align your back, and you can naturally build body and body easily.

  Some are healthy, others are inner peace, and others are weight loss. Of course, there is no difference between various motivations and goals. The original meaning of yoga is “combination”, which has the meaning of self-actualization.

Here are a few simple moves to make you beautiful and good figure NO.

1 The first group: Single lotus practice The lotus position is the basic sitting position in yoga. You can do this while watching TV. It can help move multiple ligaments of the human body and keep the meridians open.

  A.Maintain a normal sitting position with legs straight.

Succumb to the left leg, place the instep of the left foot on the groin of the right thigh, put your hands on the upper left, and gently do the upper and lower elastic exercise several times to make it finally touch the ground.

  B.
After slowly restoring the left leg, massage your hands and reset your toes.

  C.Change your right leg and gently press your right leg in accordance with your left leg action.

  D.The above action is repeated three to five times; pay attention not to press too hard each time.

  No.

2Second group: leaning against the wall, semi-ploughing “Ploughing” can be called a youthful permanent posture in yoga. We can use the wall and closet at home to properly upside down some parts of the body every day, which can make the leg shapebeautiful.

  A.Move the front towards the wall of a wall.

  B.Lean your legs up against the wall.

  C.The upper body lays naturally on the ground and stays in place.

  No.

3 third group: lowered posture This position helps the sleeping body to wake up quickly, and the whole body is filled with a large amount of fresh oxygen.

Long-term adherence can maintain fractures in the abdomen.

  A.Place your arms on the double of your head, with your fingers crossed and your palms facing inward.

  B.Inhale deeply, contract your body as much as possible in both directions, and tighten your whole body muscles for a second or two.

  C.Exhale and relax.

Repeat two or three times.

  No.

4Fourth group: The lizard pose can awaken the spine, promote blood circulation of the spine and nerves, and make each part of the body quickly start.

  After doing the tip, lay your body on your stomach.

  A.Arms support the mattress, so that the hips are up, the big and small legs are kept at about ninety degrees.

  B.
Skull and chin touch the ground, arms straight forward.

Maintain your previous natural breathing.

  C.Then return the tibia to the heel and rest for a while.

  No.

5 Fifth group: Back-end exercises Sometimes long-term desks will gradually lose the elasticity of our spine and form a humpback shape.

So, after an hour of work at the desk, we can use the high-back chair to relax.

  It can increase the elasticity of the spine and make the body more flexible. It is the best exercise method for the spine.

  A.
Place a small cushion on the back of the chair.

With your back to the chair, place the thoracic spine on the cushion.
Straighten your legs and contract your arms toward the back of your head; breathe naturally.

  B.After the restoration, relax for a while with the chest arched.

  No.
6 The sixth group: Cats gradually increase spinal elasticity after the chair, nourish the nervous system, improve blood circulation, increase digestion and eliminate excess.

  A.Hold the back of the chair with both hands, legs close together and straight.

  B.Inhale, raise your head, and contract your hip muscles to gradually collapse the front down.

Breathe naturally and hold for a few seconds.

  C.Exhale, drop your head, arch your hips, and tighten your abdominal muscles.

Breathe naturally and hold for a few seconds.
  D.Repeat five or six times.

  The key to the practice of yoga is not the posture, but the concentration of mind and the action of breathing. In any posture, you only need to follow the correct method and then reach the position where you can do it. Do n’t hurt, do n’t hold your breath.With the increase in the number of exercises, many movements will no longer stump you, and the softness and posture will become better and better. Don’t worry, calm down and let us work together in this early spring season!

Zhong Nanshan’s team developed a new version of Isatis indigotica which may be five or six times stronger than the original

Zhong Nanshan’s team developed a new version of Isatis indigotica which may be five or six times stronger than the original

On October 19, sponsored by the China Healthcare International Exchange Promotion Association and hosted by the First Affiliated Hospital of Sun Yat-sen University, the 2019 China Academician Forum was antiqued in Guangzhou, focusing on the theme of “Great Health in the Greater Bay Area”.Gu Xiaosong made separate reports.

In an interview with the media, Zhong Nanshan found that he is planning to expand research on the use of Chinese medicine for influenza prevention, and strive to find another way besides preventive measures such as vaccines.

  Talking about flu prevention “Guangdong, Hong Kong, Macao Greater Bay Area is densely populated, and flu is always a topic of interest”.

“Zhong Nanshan said,” Early this year and in July, a small flu peak occurred in our province. By the end of the year, we will spread the climate change and it may become epidemic again.

From a conventional point of view, the epidemic period in the south is generally January-February, so we should be more vigilant. ”

  To prevent influenza, Zhong Nanshan said that vaccination is still the best way, but due to lack of publicity and insufficient domestic vaccine production, only 2% of the population has been vaccinated against influenza.

  ”Can flu prevention find another way?

“Zhong Nanshan revealed that the team is currently cooperating with scientific research units in Hong Kong and plans to study the role of preventive oral administration of Chinese medicine in the response to influenza through strict controlled experiments.

“It is theoretically possible for Chinese medicine to prevent influenza, and some people are also using it empirically. All we have to do is to verify whether it is really effective with scientific methods.

“He said.

  The new technology of Banlangen Banlangen granules is a traditional Chinese medicine granule for clearing heat and detoxifying.

Academician Zhong Nanshan introduced the Banlangen “secondary development”
project jointly carried out by Guangzhou Baiyunshan Hutchison Whampoa Traditional Chinese Medicine Co., Ltd., the State Key Laboratory of Respiratory Diseases of Guangzhou Medical University and the State Key Laboratory of Chinese Medicine Quality Research of Macau University of Science and Technology.

He said that the project has been completed for nearly 10 years. At present, it is clear that there are four main components in which Radix Isatidis play a role, namely sterols, lignans, dioxazoles, and polyvalents.

They function differently, and some have a mild virus killing effect, but more are preventing the virus from entering cells or inhibiting the development of inflammation.

  Academician Zhong Nanshan led the research on the secondary development of Banlangen in Baiyun Mountain. “The secondary development of Banlangen according to the new process is currently nearing completion of the medicinal effect study. The oral dose has been reduced by 80%. Animal experiments have shown that the effect is five or six times stronger.

“Zhong Nanshan said that the new drug still has to undergo clinical trials and approvals, and the time to market is uncertain.

  Zhong Nanshan believes that purifying and “secondary development” of Banlangen is one of the important ways of modernizing Chinese medicine.

“All science is developing, and the foundation of traditional Chinese medicine is still empirical medicine. To modernize traditional Chinese medicine, we must first develop in the direction of evidence-based medicine. This road must be taken.”

  Since 2008, Guangzhou Baiyunshan Hutchison Whampoa Traditional Chinese Medicine Co., Ltd. and the State Key Laboratory of Respiratory Diseases of Guangzhou Medical University and the State Key Laboratory of Traditional Chinese Medicine Quality Research of Macao University of Science and Technology have jointly tackled many problems and conducted a large number of clinical evidence-based andbasic research.

  In 2010, Bai Yunshan and Huang, Academician Zhong Nanshan and the Macau University of Science and Technology established the “Guangdong-Macao Respiratory Pathogens Joint Research Center”.

  In 2015, Guangzhou Pharmaceutical Group signed a strategic cooperation agreement with the Guangdong-Australia Chinese Medicine Technology Industrial Park and the Macau University of Science and Technology, becoming the first famous enterprise in the park to enter the Guangdong-Macao Traditional Chinese Medicine Technology Industrial Park. This is the “Guangdong-Australia Cooperation Framework Agreement””” The first landing project.

  At the 2016 “Guangdong-Hong Kong-Macao Chinese Medicine Banlangen Research Forum and Baiyunshan Banlangen Secondary Development Research Launching Ceremony”, well-known experts and researchers from the Macau University of Science and Technology, Hong Kong University and other units conducted basic and clinical research on the antiviral activity of Baiyunshan Banlangen.Sexual summary.

By complementing the advantages at the above levels, we will work together to promote the modernization and internationalization of Chinese medicine.

  Academician Zhong Nanshan and Academician Huang Luqi discussed and answered on-site research on Baiyunshan Banlangen on the Nobel Prize Zhong Nanshan also faced the Nobel Prize in Physiology or Medicine recently announced.

He believes that China is currently estimated to have scientific development with both potential research talents and redundant budgets and venue guarantees. “It is a matter of time before more Chinese people get the Nobel Prize.

However, he also reminded that in the scientific research work, we must properly overcome the impetuous ideas that are eager to achieve success and blindly pursue quick results, and we should create an environment for scholars to feel comfortable and force scientific research.

In addition, we need to further study the transformation of results to make more results truly effective.

  Research progress on Banlangen particles in Baiyunshan Academician Zhong Nanshan After more than ten years of research, 21 compounds were isolated from Banlangen and a variety of anti-influenza virus components were found, including polysaccharides, lignans, and dioxin alkaloids.Class, etc.

And applied for 17 invention patents.

  Studies have found that isatis root polysaccharide can inhibit the hemagglutinin activity of influenza virus, that is, by inhibiting the mutation of the virus to human cells, thereby inhibiting the replication of the influenza virus and exerting an antiviral effect; at the same time, it can also inhibit the virus infecting the human body.Systemic arthritis response.

This research achievement has successfully applied for a patent, and in 2017 won the “19th China Patent Excellence Award”.

  In Isatis indigotica, a lignan anti-influenza virus compound is clematis nebulin B. It can interfere with the expression of a certain protein of the influenza virus and inhibit the growth and reproduction of the virus. Therefore, it can inhibit a variety of human influenza and avian influenza viruses.Role of Subtype Influenza Virus.

Another lignan component is larchesterol-4-O-β-D-glucoside, which inhibits the activation of influenza virus-induced antibacterial factors and exerts an inhibitory effect on the systemic inflammatory response caused by the influenza virus, so it can regulate the human body.Innate immunity.

  Studies have not found that the naphthoquinone alkaloid compound-CapparilosideA has inhibitory effects on various subtypes of influenza viruses and other common respiratory viruses, showing broad-spectrum antiviral efficacy.

Experiments show that this dioxin alkaloid can inhibit the inflammatory response caused by the influenza virus and can effectively alleviate the lung damage caused by the influenza virus.

The other is 3-naphthyl butyraldehyde, which shows more broad-spectrum antiviral activity (including A / B human influenza virus, avian influenza virus, common respiratory viruses such as parainfluenza virus, rhinovirus, etc., and potentialVirus, herpes virus, etc.) and stronger anti-flu activity in vitro and in vivo.

  (Some sources of the article: People’s Daily, Nanfang Daily) This article only represents the views of the author, and does not represent the views of the old Chinese medicine health network. If copyright issues are involved, please contact the administrator to delete!